Harriet Beecher Stowe was born on June 14, 1811, in Litchfield, Connecticut, to Lyman Beecher, a Calvinist preacher and activist in the antislavery movement, and Roxana Foote, a deeply religious woman who died when Stowe was four years old. Precocious and independent as a child, Stowe enrolled in the seminary run by her eldest sister, Catharine, where she received a traditionally "male" education. At the age of twenty-one, she moved to Cincinnati to join her father who had become the president of Lane Theological Seminary, and in 1936 she married Calvin Ellis Stowe, a professor at the seminary and an ardent critic of slavery. The Stowes supported the Underground Railroad and housed several fugitive slaves in their home. They eventually moved to Brunswick, Maine, where Calvin taught at Bowdoin College.

In 1850 congress passed the Fugitive Slave Law, prohibiting assistance to fugitives. Stowe was moved to present her objections on paper, and in June 1851 the first installment of Uncle Tom's Cabin a appeared in the antislavery journal National Era. The forty-year-old mother of seven children sparked a national debate and, as Abraham Lincoln is said to have noted, a war.

Uncle Tom's Cabin: Or, Life Among the Lowly met with mixed reviews when it appeared in book form in 1852 but soon became an international bestseller. Some critics dismissed it as abolitionist propaganda, while others hailed it as a masterpiece. The great Russian novelist Leo Tolstoy praised Uncle Tom's Cabin as "flowing from love of God and man." Stowe presented her sources to substantiate her claims in A Key to Uncle Tom's Cabin: Presenting the Original Facts and Documents Upon Which It Is Based, published in 1853. Another antislavery novel, Dred: A Tale of the Great Dismal Swamp, appeared in 1856 but was received with neither the notoriety nor the success of Uncle Tom's Cabin.

Stowe fueled another controversy in The True Story of Lady Byron's Life (1869), in which she accused the poet Lord Byron of having an incestuous love affair with his half sister, Lady Byron. She also took up the topic of domestic culture in works that include The New Housekeeper's Manual (1873), written with her sister Catharine. Stowe died on July 1, 1896, at age eighty-five, in Hartford, Connecticut.

Author biography from the Barnes & Noble Classics edition of Uncle Tom's Cabin.