Applied Biocatalysis in Specialty Chemicals and Pharmaceuticals

by David C. Demirjian, Badal C. Saha

Overview

Written for a wide variety of biotechnologists, this book provides a major review of the state-of-the-art in bioethanol production technologies, enzymatic biomass conversion, and biodiesel. It also provides a detailed explanation of a breakthrough in photosynthetic water splitting which could result in a doubling of the efficiency of solar energy conversion by green plants. The book covers production of lactic acid, succinic acid, 1,3-propanediol, 2,3-butanediol, and polyhydroxybutyrate and xylitol. It also includes a chapter on synthesis-gas fermentation.

Product Details

ISBN-13:	9780841236790
Publisher:	American Chemical Society
Publication date:	12/28/2000
Series:	ACS Symposium Series , #776
Pages:	306
Product dimensions:	5.80(w) x 8.90(h) x 0.70(d)

Table of Contents

Preface
Overview
1. Advances in Enzyme Development and Applied Industrial Biocatalysis, Badal C. Saha and David C. Demirjian
Selected Discovery, Characterization, and Engineering
2. Selected Historical Perspectives in Biocatalysis, 1752-1960, S.L. Neidleman
3. Screening of Hydrolase Libraries Using pH-Shift Reagents: Rapid Evaluation of Enantioselectivity, Francisco Moris-Varas, Laura Hartman, Amit Shah, and David C. Demirjian
4. Selection of Saprophytic Bacteria and Characterization of Their Fatty Acid Bioconversions during Compost Formation, T.M. Kuo and T. Kaneshiro
5. D-Phenylalanine Biosynthesis Using Escherichia Coli: Creation of a New Metabolic Pathway, Paul P. Taylor, Nigel J. Grinter, Shelly L. McCarthy, David P. Pantaleone, Jennifer L. Ton, Roberta K. Yoshida, and Ian G. Fotheringham
6. Improvement of Enzyme Character by Gene Shuffling, Kiyoshi Hayashi, Qin Wang, Satoru Nirasawa, Tsuyoshi Simonishi, Motomitsu Kitaoka, and Satoshi Kaneko
Applications: Specialty Chemicals
7. Bioconversion of Unsaturated Fatty Acids to Value-Added Products, Ching T. Hou
8. The Nicotinamide Cofactors: Applications in Biotechnology, Hugh O'Neill and Jonathan Woodward
9. Production of Galacto-Oligosaccharides from Lactose by Immobilized *B-Galactosidase, Shang-Tian Yang and Julia A. Bednarcik
10. Phyllosilicate Sol-Gel Immobilized Enzymes: Their Use as Packed Bed Column Bioreactors, A.F. Hsu, T.A. Foglia, K. Jones, and S. Shen
11. Biocatalytic Preparation of D-Amino Acids, David P. Pantaleone, Paul P. Taylor, Tamara D. Dukes, Kurt R. Vogler, Jennifer L. Ton, Daniel R. Beacom, Shelly L. McCarthy, Bruce E. Meincke, L. Kirk Behrendt, Richard F. Senkpeil, and Ian G. Fotheringham
Applications: Pharmaceutical
12. Application of Biocatalysis in Chemical Process Development: A Few Case Studies, Weiguo Liu
13. Method for the Stereoselective Production of Chiral Vicinal Aminoalcohols: Establishing Two Chrial Centers by Diastereoselective Reduction, J. David Rozzell
14. Stereoselectivity of Penicillin Acylase Catalyzed Ester Hydrolysis, Ravindra S. Topgi
15. Synthesis of Chiral Pharmaceutical Intermediates by Oxidoreductases, Ramesh N. Patel and Ronald L. Hanson
16. Production of Chiral Amines with *w-Transaminase, Jong-Shik Shin and Byung-Gee Kim
17. Enantiorecognition of Chiral Acids by Candida rugosa Lipase: Two Substrate Binding Modes Evidenced in an Organic Medium, Per Berglund, Maria Christiernin, and Erik Hedenström
Author Index
Subject Index

Editorial Reviews

"this excellent book, edited by Saha and Demirjan, provides an update on recent research underpinning the application of enzymes for the synthesis of speciality chemicals and pharmaceuticals."—Chemistry and Industry

From the Publisher