Table of Contents
Foreword
Section I Basic Principles
Part I Basic Embrology of Cleft Lip and Palate
1. Formation of the Primary Palate, Geoffrey H. Sperber, University of Alberta
2. Palatogenesis: Closure of the Secondary Palate, Geoffrey H. Sperber, University of Alberta
3. Genes Implicated in Lip and Palate Development, Samuel S. Chong, Felicia S.H. Cheah, and Ethylin Wang Jabs SC, FC: National University of Singapore; EJ: John Hopkins University
Part II Clinical Features of Cleft Lip and Cleft Palate
4. The Orofacial Exampination: Normal and Abnormal Findings, Eric A. Wulfsberg, University of Maryland
5. Classification and Description of Nonsyndromic Clefts, Howard M. Saal, University of Cincinnati
6. Syndromes with Orofacial Clefting, M. Michael Cohen, Jr., Dalhousie University
7. Morphometric Characteristics of Subjects with Oral Facial Clefts and Their Relatives, Richard E. Ward, Elizabeth S. Moore, and James K. Hartsfield, Jr., RW: Indiana University and Purdue University; EM, JH: Indiana University School of Dentistry
8. Craniofacial Morphology and Growth in Infants and Young Children with Cleft Lip and Palate, Sven Kreiborg and Nuno V. Hermann, University of Copenhagen (both)
Part III Epidemiology of Cleft Lip and Palate
9. Methodological Issues in Epidemiological Studies of Oral Clefts, Kaare Christensen, university of Southern Denmark (Odense)
10. Exposure Assessment in Studies of Oral Clefts, Martha M Werler, Boston University School of Public Health
11. Birth Defects Surveillance Systems and Oral Clefts, Adolfo Correa and Larry Edmonds, Centers for Disease Control and Prevention (both)
12. Epidemiology of Oral Clefts: An International Perspective, Peter A. Mossey and Julian Little, PM: Dundee Dental School; JL: University of Aberdeen
13. Environmental Risk Factors and Oral Clefts, Catherine Hayes, Harvard School of Dental Medicine
14. Maternal Nutrition and Oral Clefts, Ronald G. Munger, Utah State University
15. Experimental Models for the Study of Oral Clefts, Barbara D. Abbott, Environmental Protection Agency
Part IV Genetics of Cleft Lip and Palate
16. The Human Genome Project, Janee Gelineau-van Waes and Richard H. Finnell, JG: Nebraska Medical Center; RF: Texas A & M University
17. The Role of Twin Studies in Oral Clefts Research, Laura E. Mitchell, University of Pennsylvania
18. Segregation Analyses, Mary L. Marazita, University of Pittsburgh Schools of Dental Medicine and Public Health
19. Mode of Inheritance of Oral Clefts, Laura E. Mitchell, University of Pennsylvania
20. Associate Studies, Mary L. Marazita and Katherine Neiswanger, MM: see #18, KN: University of Pittsburgh School of Dental Medicine
21. Locating Genes for Oral Clefts in Humans, Diego F. Wyszynski, Boston University Schools of Medicine and Public Health
22. Mapping Studies in Animal Models, Diana M. Juriloff, University of British Columbia
23. Gene-Environment Interaction and Risk to Oral Clefts, Joanna S. Zieger and Terri H. Beaty, John Hopkins University Bloomberg School of Public Health (both)
Section II Treatment
24. Developing a Cleft Palate or Craniofacial Team, Ronald P. Strauss, University of North Carolina
25. Health Care for Children with Cleft Lip and Palate: Comprehensive Services and Infant Feeding, John A. Nackashi, E. Rosellen Dedlow, and Virginia Dixon Wood, University of Florida (all)
26. The Staging of Cleft Lip and Palate Reconstruction: Infancy through Adolescence, Jeffrey C. Posnick and Ramon L. Ruiz, JP: Georgetown University; RR: University of North Carolina
27. Evaluation and Management of Speech, Language, and Articulation Disorders, John E. Riski, Children's Healthcare of Atlanta
28. Pediatric Dental Care, Frank Farrington, Virginia Commonwealth University School of Dentistry
29. The Role of the Orthodontist in the Management of Patients with Cleft Lip and/or Palate, Andrew C. Lidral and Katherine W.L. Vig, AL: University of Iowa; KV: The Ohio State University
30. Otolaryngologic Needs of Individuals with Oral Clefts, Patrick J. Antonelli, University of Florida
31. Genetic Counseling and Interpretation of Risk Figures, Carmella S. Stadter, University of Maryland
32. The Psychological Care of Children with Cleft Lip and Palate in the Family, Kathleen A. Kapp-Simon, Northwestern University Cleft Lip and Palate Institute
33. International Surgical Missions, S.T. Lee, Singapore General Hospital
34. Evidence-Based Care for Children with Cleft Lip and Palate, William C. Shaw and Gunvor Semb, WS: University Dental Hospital of Manchester (both)
Section III Public Health Issues
35. Prevention of Oral Clefts Through the Use of Folic Acid and Multivitamin Supplements: Evidence and Gaps, Andrew E. Czeizel, Foundation for the Community Control of Hereditary Diseases(Budapest, Hungary)
36. The Costs of Cleft Lip and Palat: Personal and Societal Implications, Nancy W. Berk and Mary L. Marazita, NB: University of Pittsburgh School of Dental Medicine, MM: see #18
37. Insurance and Coverage of Care, David A. Billmire, Children's Hospital Medical Center (Cincinnati, Ohio)
38. Parent's Perspective on Cleft Lip and Palate, Jane Nicholson, University of Michigan
39. Ethical Issues in the Care of Children with Craniofacial Conditions, Ronald P. Strauss, University of North Carolina
40. Translating Research Findings into Public Health Action and Policy, Richard S. Onley, Emory University
41. Educating the Practitioner and the Public, Marilyn C. Jones, University of California, San Diego
42. Innovative Attempts Toward International Cooperation, Negato Ntsume, David S. Precious, and Hermann F. Sailer NN: Aichi-Gakuin University, Japan; DP: Dalhousie University; HS: University Hospital(Zurich, Switzerland)
Appendix: Internet Resources
