Cognitive and Behavioral Abnormalities of Pediatric Diseases / Edition 1

by Ruth Nass, MD, Yitzchak Frank, MD

Overview

This book provides a detailed account of intellectual, other neuropsychological and behavioral manifestations of general pediatric diseases. The conditions discussed include the whole range of pediatric diseases - genetic syndromes, other congenital conditions, metabolic, endocrine, gastrointestinal, infectious, immunologic, toxic, trauma, and neoplastic, as well as sensory disabilities including deafness and blindness. Although the book is not intended to discuss cognitive and behavioral manifestations of conditions usually considered to be primary neurological disease, some of those, including cerebral palsy, muscular dystrophy, myotonic dystrophy and epilepsy, are included.

Where possible, a "translational" approach is used, linking the behavioral and cognitive manifestations of these conditions, to the underlying structural, chemical or genetic abnormalities and their effect on the brain, and, in turn, on behavior and cognition. At the same time, included are significant psychosocial factors. Together, those factors have a major effect on patients' performance, including school performance, and on their families.

This book is unique in its extensive coverage of the major pediatric conditions and of the detailed neurological, neuropsychological and behavioral aspects of each condition.

Product Details

ISBN-13:	9780195342680
Publisher:	Oxford University Press, USA
Publication date:	04/12/2010
Pages:	704
Product dimensions:	8.70(w) x 11.00(h) x 1.60(d)

About the Author

Dr Nass is a pediatric neurologist with a particular interest in behavioral neurology. She has an active clinical practice where she sees child with autism, ADHD and other neuropsychiatric disorders, as well as children with migraines and other neurological disorders. Her research interests currently focus on the development of hemispheric specialization and aspects of autism, particularly the relationship with seizures, neurological disorders like tuberous sclerosis, and stereotypy patterns and their relationship to Tourettes.

Dr Frank is a pediatric Neurologist with clinical and teaching reponsibilities at Mount Sinai Medical School, in New York. His clinical practice includes in-patient hospital consultations, and outpatient faculty practice at Mount Sinai Medical Center. His teaching responsibilities include teaching of medical students, pediatric and neurology residents at the medical school. In addition he has a specific interest in pediatric behavioral neurology, including Learning Disabilities, ADHD and Autism. His current research interest is in the behavioral aspects of Learning Disabilities.

Table of Contents

I. INTRODUCTION
1. General Effects of Pediatric Diseases on Cognition and Behavior, Mari Hysing and Astri J. Lundervold

II. AUTOIMMUNE DISEASES
2. Double syndromes: Autism Associated with Genetic, Medical and Metabolic Disorders, Christopher Gillberg
3. Cognitive and Psychiatric Manifestations of Childhood-Onset Systemic Lupus Erythematotus, Deborah M. Levy and Gail S. Ross

III. CARDIAC DISEASE
4. The Impact of Congenital Heart Disease on Cognitive and Behavioral functioning, Jo Wray

IV. ENDOCRINE DISEASE
5. Addison Disease, Patricia I. Rosebush, Rebecca A. Anglin, and Michael F. Mazurek
6. Cognitive and Behavioral Aspect of Congenital Adrenal Hyperplasia, Sheri A. Berenbaum
7. Type 1 Diabetes, Tamara Hershey
8. Cognitive and Behavioral Complications of Congenital Hypothyroidism, Ruth D. Nass
9. Short Stature and the Relationship to Male Mental Health Status, Elsie Mobbs
10. Psychological Effects of Precocious and Delayed Puberty, Laura M. DeRose, Julia A. Graber, and Jeanne Brooks-Gunn

V. GASTROINTESTINAL DISEASES
11. Cognitive and Behavioral Manifestations of Celiac Disease, Helmut Niederhofer, Klaus Pittschieler, and Yitzchak Frank
12. Cognitive and Behavioral Abnormalities Associated with Liver Disease and Wilson Disease, Yitzchak Frank

VI. GENETIC SYNDROMES
13. Down Syndrome, Stephen R. Hooper, Julie Hammer, and Joanne E. Roberts
14. Fragile X: A Family of Disorders, Ann M. Mastergeorge, Jacky Au, and Randi Hagerman
15. Klinefelter Syndrome, Christine M. Temple
16. Noonan Syndrome, Ellen Wingbermühle, Ineke van der Burgt, Joe Egger, and Willem Verhoeven
17. Prader-Willi Syndrome, Jennifer Zarcone and Sarah Spencer Welsh
18. Neurologic Aspects of the Smith-Magenis Syndrome, Andrea L. Gropman, Ann C. M. Smith, Wallace Duncan
19. Cognitive and Behavioral Manifestations in Turner Syndrome, Aysenil Belger, Sarah J. Hart, Marsha L. Davenport, Stephen R. Hooper
20. Velo-cardio-facial Syndrome, Kevin M. Antshel, Robert Shprintzen, Wanda Fremont, Anne Marie Higgins, and Wendy R. Kates
21. Williams Syndrome, Judy Reilly, Philip Lai, Josie Bernicot, and Ursula Bellugi

VII. HEMATOLOGIC DISEASE
22. Neurocognitive Outcomes in Sickle Cell Disease, F. Daniel Armstrong, Steven Pavlakis, Maria L. Goldman, Winsome Thompson, Anai Cuadra, and Wendy Sulc

VII. INFECTIONS
23. Pediatric Human Immunodeficiency Virus, Elizabeth J. Willen, Anai Cuadra, and Lisa Jacobson
24. Lyme Disease, Anita L. Belman and Thomas Preston
25. Congenital Infections, Yushiro Yamashita

IX. METABOLIC DISEASE
26. Neurological and Cognitive Consequences of Nephropathic Cystinosis, Doris A. Trauner
27. Cognitive and Behavioral Manifestations of Classical Galactosemia, Kevin M. Antshel
28. Cognitive and Behavioral Manifestations of Disorders of Homocysteine Metabolism, Elaine Murphy
29. Phenylketonuria, Virdette L. Brumm and Richard Koch
30. Urea Cycle Disorders, Bendan Lanpher

X. NEUROCUTANEOUS SYNDROMES
31. Neurofibromatosis Type 1: Cognitive and Behavioral Phenotype: Diagnosis and Treatment, Maria T. Acosta
32. Tuberous Sclerosis Complex, Paolo Curatolo, Elisa D'Agati, and Romina Moavero

XI. NEONATAL DISORDERS
33. Outcome of Neonates with Hyperbilirubinemia, Gail S. Ross and Alfred N. Krauss
34. Intrauterine Growth Restriction, Ronny Geva
35. Prematurity: Impact on Neurodevelopmental and Behavioral Outcomes, Betty R. Vohr

XII. NEOPLASTIC DISEASE
36. Neurocognitive Outcomes in Childhood Cancer: Effects of Disease and Treatment on Brain Development and Learning, F. Daniel Armstrong, Maria L. Goldman, Wendy Sulc, Winsome Thompson, and Anai Cuadra
37. Neurocognitive Effects of Solid Organ Transplantation, Nataliya Zelikovsky, Debra S. Lefkowitz, and Emily M. Fredericks

XIII. PERIPHERAL/NEUROMUSCULAR DISEASE
38. Familial Dysautonomia, Felicia B. Axelrod
39. The Dystrophinopathies, Virginia J. Hinton
40. Myotonic Dystrophy, Stefan Winblad, Anne-Berit Ekström, and Giovanni Meola

XIV. PULMONARY DISEASE
41. Asthma and Cystic Fibrosis, Robert Hilt, Alison Leary, and Kari Kawakami Hancock

XIV RENAL DISEASE
42. Cognitive and Behavioral Challenges of Chronic Kidney Disease, Phil Icard, Stephen R. Hooper, and Debbie S. Gipson

XVI. SENSORY DISORDERS
43. The Behavioral and Cognitive Manifestations of Blindness in Children, Linda Pring and Valerie Tadi?
44. Cognitive and Behavioral Complications of Deafness, Barry Wright

XVII. SLEEP DISORDERS
45. Neuropsychological Consequences of Sleep-Disordered Breathing, Jennifer Janusz and Ann Halbower

XVIII. TOXINS
46. Fetal Alcohol Spectrum Disorders, John C. Thorne, Tracy Jirikowic, Allison Brooks, and Julian Davies
47. Prenatal Drug Exposure: Childhood Behavior and Cognitive Functioning, Thitinart Sithisarn and Henrietta S. Bada
48. Intrauterine and Postnatal Exposure to Tobacco and to Secondhand Smoke and Child Cognitive and Behavioral Development, Elizabeth Poole-Di Salvo and Michael Weitzman
49. Cognitive and Behavioral Manifestations of Lead, Hugh L. Evans
50. Cognitive Complications of Mercury Exposure, Hugh L. Evans
51. Pediatric Carbon Monoxide Poisoning, Ramona O. Hopkins

XIX. TRAUMA
52. Neurobiological, Cognitive, and Behavioral Consequences of Child Maltreatment, Katherine C. Pears, Jacqueline Bruce, and Philip A. Fisher
53. Neuropsychological and Psychiatric Outcomes of Traumatic Brain Injury in Children, Jeffrey E. Max, Farheen Ibrahim, and Harvey Levin

Index

Editorial Reviews

Reviewer: Christopher J Graver, PhD, ABPP-CN(Madigan Healthcare System)
Description: Although treating the physical aspects of disease is often foremost in the minds of patients and clinicians, the cognitive and behavioral consequences are often more enduring. This book explores these aspects of pediatric disease.
Purpose: The aim of this book is to review the literature on pediatric illness and the directly resulting cognitive and behavioral effects of brain dysfunction, as opposed to secondary emotional and social effects.
Audience: The authors do not indicate a particular audience, but a wide variety of readers will find this compelling, including child and school psychologists, psychiatrists, neuropsychologists, pediatricians, and pediatric neurologists. The editors and authors are well known and respected in their fields.
Features: The book begins with a brief overview of common consequences of pediatric diseases. The remainder of the book is separated into major sections of medical diseases, including diseases of an autoimmune, cardiac, endocrine, gastrointestinal, genetic, hematologic, infection, metabolic, neurocutaneous, neonatal, neuroplastic, neuromuscular, pulmonary, renal, sensory, sleep, toxic, and traumatic nature. As is evident, there is vast coverage of pediatric disease for many of the most commonly encountered problems. Each of these chapters describes the disease and its pathogenesis and has extensive subsections on neuropsychological profiles and other neurobehavioral abnormalities. The neuropsychological sections address specific cognitive domains to provide readers with a typical neuropsychological profile. Academic achievement is sometimes treated as a separate section to provide more specific and detailed information about this aspect of development. When appropriate, the chapters also cover diagnosis and screening, neurologic and radiologic abnormalities, and treatment. The chapters are well organized, easy to read, and contain useful tables and figures, but the print quality could be better in some cases (e.g., neuroimaging). The references are abundant and current to last year.
Assessment: This is an essential guide to the neuropsychological and neurobehavioral consequence of pediatric diseases for healthcare providers working with a pediatric population. Psychologists and neuropsychologists in particular would be remiss to evaluate and/or treat children without this book readily at hand.

Doody's Review Service

"This is an essential guide to the neuropsychological and neurobehavioral consequence of pediatric diseases for healthcare providers working with a pediatric population." —Doody's

"This is a well-bound and sturdy, large format text. The page layout is attractive, and the typeface is easy to read. Tables, black-and-white illustrations, and figures are used sparingly but effectively. There is an extensive index that appears to be accurate and proved useful to the reviewer. Child neurologists and their trainees will find this a valuable reference." —Pediatric Neurology

From the Publisher

Reviewer:This is an essential guide to the neuropsychological and neurobehavioral consequence of pediatric diseases for healthcare providers working with a pediatric population. Psychologists and neuropsychologists in particular would be remiss to evaluate and/or treat children without this book readily at hand.
Description:
Purpose:Although treating the physical aspects of disease is often foremost in the minds of patients and clinicians, the cognitive and behavioral consequences are often more enduring. This book explores these aspects of pediatric disease.
Audience:The aim of this book is to review the literature on pediatric illness and the directly resulting cognitive and behavioral effects of brain dysfunction, as opposed to secondary emotional and social effects.
Features:The authors do not indicate a particular audience, but a wide variety of readers will find this compelling, including child and school psychologists, psychiatrists, neuropsychologists, pediatricians, and pediatric neurologists. The editors and authors are well known and respected in their fields.
Assessment:The book begins with a brief overview of common consequences of pediatric diseases. The remainder of the book is separated into major sections of medical diseases, including diseases of an autoimmune, cardiac, endocrine, gastrointestinal, genetic, hematologic, infection, metabolic, neurocutaneous, neonatal, neuroplastic, neuromuscular, pulmonary, renal, sensory, sleep, toxic, and traumatic nature. As is evident, there is vast coverage of pediatric disease for many of the most commonly encountered problems. Each of these chapters describes the disease and its pathogenesis and has extensive subsections on neuropsychological profiles and other neurobehavioral abnormalities. The neuropsychological sections address specific cognitive domains to provide readers with a typical neuropsychological profile. Academic achievement is sometimes treated as a separate section to provide more specific and detailed information about this aspect of development. When appropriate, the chapters also cover diagnosis and screening, neurologic and radiologic abnormalities, and treatment. The chapters are well organized, easy to read, and contain useful tables and figures, but the print quality could be better in some cases (e.g., neuroimaging). The references are abundant and current to last year.