Genomes

by Hillary E. Sussman, Maria A. Smit

Overview

George Beadle was a towering scientific figure whose work from the 1930s to 1960 marked the transition from classical genetics to the molecular era. Among other distinctions, he made the pivotal, Nobel Prize Swinning discovery with Edward Tatum that the role of genes is to specify proteins. From 1946 to 1960 he led the Caltech Biology Division, rebuilding it to a powerhouse in molecular biology, and afterwards became a successful President of the University of Chicago. This is the first biography of a giant of genetics, written by two of the field's most distinguished contributors, Paul Berg and Maxine Singer.

Product Details

ISBN-13:	9780879698072
Publisher:	Cold Spring Harbor Laboratory Press
Publication date:	03/24/2006
Series:	Cold Spring Harbor Monograph Series , #46
Edition description:	New Edition
Pages:	488
Product dimensions:	5.90(w) x 8.80(h) x 0.80(d)

Table of Contents

Preface
Foreword, J.D. Watson
1. Insights on Biology and Evolution from Microbial Genome Sequencing
2. Changing Perspectives in Yeast Research Nearly a Decade after the Genome Sequence
3. Genomics of the Fungal Kingdom: Insights into Eukaryotic Biology
4. The Arabidopsis Genome: A Foundation for Plant Research
5. Grains of Knowledge: Genomics of Model Cereals
6. Genomics in Caenorhabditis elegans: So Many Genes, Such a Little Worm
7. Drosophila melanogaster: A Case Study of a Model Genomic Sequence and Its Consequences
8. Unraveling Genomic Regulatory Networks in the Simple Chordate, Ciona intestinalis
9. Fish Genomics and Biology
10. Xenomics
11. Chicken Genome: Current Status and Future Opportunities
12. Advances in Livestock Genomics: Opening the Barn Door
13. The Canine Genome
14. Impact of Genomics on Research in the Rat
15. The Mouse Genome
16. Genomics of the Future: Identification of Quantitative Trait Loci in the Mouse
17. Comparing the Human and Chimpanzee Genomes: Searching for Needles in a Haystack
18. Structure and Function of the Human Genome
19. Emerging Technologies in DNA Sequencing
20. Genome Annotation Past, Present, and Future: How to Define an Open Reading Frame at Each Locus
Index

Editorial Reviews

This collection of 20 chapters was originally published in a 2005 issue of the journal Genome Research to commemorate the 10th anniversary of its inception. With contributions spanning a diverse array of organisms from microbes to humans, leaders in the field describe their work and its relevance to our understanding of the structure and function of genomes in what is now known as the 'postgenomic age.' ... As we embrace a future of databases of hundreds of genomes, this volume is an exemplary treatment of how biological questions in comparative genomics should be portrayed.

The Quarterly Review of Biology