Handbook of Biomedical Nonlinear Optical Microscopy
The Handbook of Biomedical Nonlinear Optical Microscopy provides comprehensive treatment of the theories, techniques, and biomedical applications of nonlinear optics and microscopy for cell biologists, life scientists, biomedical engineers, and clinicians. The chapters are separated into basic and advanced sections, and provide both textual and graphical illustrations of all key concepts. The more basic sections are aimed at life scientists without advanced training in physics and mathematics, and tutorials are provided for the more challenging sections. The first part of the Handbook introduces the historical context of nonlinear microscopy. The second part presents the nonlinear optical theory of two- and multiphoton excited fluorescence (TPE, MPE) spectroscopy, second and third harmonic generation (SHG, THG) spectroscopy, and coherent anti-Stokes Raman spectroscopy (CARS). The third part introduces modern microscopic and spectroscopic instrumentation and techniques that are based on nonlinear optics. The fourth part provides key applications of nonlinear microscopy to the biomedical area: neurobiology, immunology, tumor biology, developmental biology, dermatology, and cellular metabolism. There are also chapters on nonlinear molecular probes, cellular damage, and nanoprocessing.
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Handbook of Biomedical Nonlinear Optical Microscopy
The Handbook of Biomedical Nonlinear Optical Microscopy provides comprehensive treatment of the theories, techniques, and biomedical applications of nonlinear optics and microscopy for cell biologists, life scientists, biomedical engineers, and clinicians. The chapters are separated into basic and advanced sections, and provide both textual and graphical illustrations of all key concepts. The more basic sections are aimed at life scientists without advanced training in physics and mathematics, and tutorials are provided for the more challenging sections. The first part of the Handbook introduces the historical context of nonlinear microscopy. The second part presents the nonlinear optical theory of two- and multiphoton excited fluorescence (TPE, MPE) spectroscopy, second and third harmonic generation (SHG, THG) spectroscopy, and coherent anti-Stokes Raman spectroscopy (CARS). The third part introduces modern microscopic and spectroscopic instrumentation and techniques that are based on nonlinear optics. The fourth part provides key applications of nonlinear microscopy to the biomedical area: neurobiology, immunology, tumor biology, developmental biology, dermatology, and cellular metabolism. There are also chapters on nonlinear molecular probes, cellular damage, and nanoprocessing.
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Handbook of Biomedical Nonlinear Optical Microscopy

Handbook of Biomedical Nonlinear Optical Microscopy

Handbook of Biomedical Nonlinear Optical Microscopy

Handbook of Biomedical Nonlinear Optical Microscopy

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$179.99 

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Overview

The Handbook of Biomedical Nonlinear Optical Microscopy provides comprehensive treatment of the theories, techniques, and biomedical applications of nonlinear optics and microscopy for cell biologists, life scientists, biomedical engineers, and clinicians. The chapters are separated into basic and advanced sections, and provide both textual and graphical illustrations of all key concepts. The more basic sections are aimed at life scientists without advanced training in physics and mathematics, and tutorials are provided for the more challenging sections. The first part of the Handbook introduces the historical context of nonlinear microscopy. The second part presents the nonlinear optical theory of two- and multiphoton excited fluorescence (TPE, MPE) spectroscopy, second and third harmonic generation (SHG, THG) spectroscopy, and coherent anti-Stokes Raman spectroscopy (CARS). The third part introduces modern microscopic and spectroscopic instrumentation and techniques that are based on nonlinear optics. The fourth part provides key applications of nonlinear microscopy to the biomedical area: neurobiology, immunology, tumor biology, developmental biology, dermatology, and cellular metabolism. There are also chapters on nonlinear molecular probes, cellular damage, and nanoprocessing.

Product Details

ISBN-13: 9780198036821
Publisher: Oxford University Press
Publication date: 05/19/2008
Sold by: Barnes & Noble
Format: eBook
File size: 15 MB
Note: This product may take a few minutes to download.

About the Author

Professor Peter T. C. So is a Professor of Mechanical Engineering and Biological Engineering at the Massachusetts Institute of Technology (MIT), Cambridge, MA. He received a B.S. degree in physics and mathematics in 1986 from the Harvey Mudd College and a Ph.D. degree in physics in 1992 from Princeton University. Professor So joined MIT as a faculty member in 1996. Professor So has published over 75 research papers in refereed journals, over 30 refereed conference proceedings, many book chapters, and numerous scientific abstracts. He is also the co-inventor of five patents related to microscopy and instrumentation. Barry R. Masters is a visiting scientist in the Department of Biological Engineering at the Massachusetts Institute of Technology and a visiting scholar in the Department of the History of Science at Harvard University. He was formerly a professor in anatomy at the Uniformed Services University of the Health Sciences. He is a Fellow of the Optical Society of America (OSA), the International Society for Optical Engineering (SPIE), and the American Association for the Advancement of Science (AAAS). Professor Masters has published 81 refereed research papers and 128 book chapters and articles. He is the editor or author of Noninvasive Diagnostic Techniques in Ophthalmology; Medical Optical Tomography: Functional Imaging and Monitoring; Selected Papers on Confocal Microscopy; Selected Papers on Optical Low-Coherence Reflectometry and Tomography; Selected Papers on Multiphoton Excitation Microscopy; Confocal Microscopy and Multiphoton Excitation Microscopy: the Genesis of Live Cell Imaging; and with Peter So, Handbook of Biomedical Nonlinear Optical Microscopy. Professor Masters is a member of the editorial board of Graefe's Archive for Clinical and Experimental Ophthalmology. His research interests include the development of in vivo microscopy of the human eye and skin, biomedical imaging and spectroscopy, and the fractal analysis of branching vascular patterns.

Table of Contents

List of Contributors
Foreword, Watt Webb
Part I. Historical Development of Nonlinear Optical Spectroscopy and Microscopy
Introduction to Part I: Historical Development of Nonlinear Optical Microscopy and Spectroscopy, Barry R. Masters
Chapter 1. The Genesis of Nonlinear Optical Microscopies and Their Impact on Modern Developments, Barry R. Masters and Peter T. C. So
Chapter 2. The Scientific Life of Maria Göppert-Mayer, Barry R. Masters
Chapter 3. The History of Perturbation Theory from Astronomy to Quantum Mechanics, Barry R. Masters
Chapter 4. English Translations of and Translator's Notes on Maria Göppert-Mayer's Theory of Two-Quantum Processes, Barry R. Masters
Part II. Nonlinear Optical Spectroscopy
Introduction to Part II: Nonlinear Optical Spectroscopy, Robert W. Boyd and Barry R. Masters
Chapter 5. Classical and Quantum Theory of One-Photon and Multiphoton Fluorescence Spectroscopy, Barry R. Masters and Peter T. C. So
Chapter 6. Second- and Higher-Order Harmonic Generation, Robert W. Boyd
Chapter 7. Theory of Spontaneous and Coherent Raman Scattering, Eric O. Potma and X. Sunney Xie
Part III. Nonlinear Optical Instruments for Microscopic Imaging and Analysis
Introduction to Part III: Nonlinear Optical Instruments for Microscopic Imaging and Analysis: Review and Forecast, Peter T. C. So and Daekeun Kim
Chapter 8. Laser Sources for Non-Linear Microscopy, John Girkin
Chapter 9. Ultrashort Optical Pulse Delivery for Nonlinear Optical Microscopy, Peter T.C. So and Daekeun Kim
Chapter 10. An Optical Design Primer for Nonlinear Optical Microscopy, Peter T. C. So and Daekeun Kim
Chapter 11. Image Formation in Multiphoton Fluorescence Microscopy, Min Gu
Chapter 12. Signal Detection and Processing in Nonlinear Optical Microscopes, Siavash Yazdanfar and Peter T. C. So
Chapter 13. Multiphoton Excitation of Fluorescent Probes, Chris Xu and Warren R. Zipfel
Chapter 14. Multiphoton-Induced Cell Damage, Karsten König
Chapter 15. Applications of Second-Harmonic Generation Microscopy, Jerome Mertz
Chapter 16. Second-Harmonic Generation Imaging Microscopy of Structural Protein, Paul J. Campagnola
Chapter 17. Coherent Anti-Stokes Raman Scattering (CARS) Microscopy: Instrumentation and Applications, Eric O. Potma and X. Sunney Xie
Chapter 18. High-speed Imaging Using Multiphoton Excitation, Ki H. Kim, Karsten Bahlmann, Timothy Ragan, Daekeun Kim, and Peter T. C. So
Chapter 19. Nonlinear Multi-Spectral Optical Imaging Microscopy: Concepts, Instrumentation, and Applications, Sebastian Wachsmann-Hogiu and Daniel L. Farkas
Chapter 20. Multiphoton Polarization Microscopy, Yen Sun, Wen Lo, Jiunn Wen Su, Sung-Jan Lin, Shiou-Hwa Jee, and Chen-Yuan Dong
Chapter 21. Lifetime-Resolved Imaging in Nonlinear Microscopy, Wolfgang Becker and Axel Bergmann
Chapter 22. Förster Resonance Energy Transfer (FRET), Barry R. Masters and Peter T. C. So
Chapter 23. Two-Photon Förster Resonance Energy Transfer (FRET) Microscopy, Ye Chen, Horst Wallrabe and Ammasi Periasamy
Chapter 24. Diffraction Unlimited Far-Field Fluorescence Microscopy, Andreas Schönle, Jan Keller, Benjamin Harke, and Stefan W. Hell
Chapter 25. Two-Photon Fluorescence Correlation Spectroscopy, Suzette Pabit and Keith Berland
Chapter 26. Photobleaching and Recovery with Nonlinear Microscopy, Edward Brown, Ania Majewska, and Rakesh K. Jain
Chapter 27. Femtosecond Laser Nanoprocessing, Karsten König
Part IV. Biomedical Applications of Nonlinear Optical Microscopy
Introduction to Part IV: Biomedical Applications of Nonlinear Optical Microscopy, Bruce J. Tromberg
Chapter 28. Pioneering Applications Of Two-Photon Microscopy To Mammalian Neurophysiology: Seven Case Studies, Q.-T. Nguyen, G. O. Clay, N. Nishimura, C. B. Schaffer, L. F. Schroeder, P. S. Tsai, and D. Kleinfeld
Chapter 29. Applications of Non-Linear Intravital Microscopy in Tumor Biology, Rakesh K. Jain, Michael F. Booth, Timothy P. Padera, Lance L. Munn, Dai Fukumura, and Edward Brown
Chapter 30. Immunology Based on Nonlinear Optical Microscopy, Ian Parker and Michael D. Cahalan
Chapter 31. Multiphoton Imaging in Animal Development, Irina V. Larina and Mary E. Dickinson
Chapter 32. Nonlinear Microscopy Applied to Dermatology, Barry R. Masters and Peter T. C. So
Chapter 33. Cellular Metabolism Monitored by NAD(P)H Imaging with Two-Photon Excitation Microscopy, Barry R. Masters
Index

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