Hans Krebs: Architect of Intermediary Metabolism, 1933-1937

by Frederic Lawrence Holmes

Overview

Reconstructs the investigative pathway and the life of Hans Krebs, from the time of his arrival in England in 1933 until 1937, when he made the discovery for which he is best known--the formulation of the citric acid cycle.

Product Details

ISBN-13:	9780195076578
Publisher:	Oxford University Press, USA
Publication date:	05/28/1993
Series:	Monographs on the History and Philosophy of Biology Series
Pages:	504
Product dimensions:	6.50(w) x 9.56(h) x 1.48(d)

About the Author

Yale University School of Medicine

Table of Contents

1. A New Home for a Career
2. Laboratory Life in Cambridge
3. Progress Under Pressure
4. New Moves
5. Arrivals and Partings
6. The "Great Work"
7. Relocations and Dismutations
8. Main Routes and Carriers
9. Full Circle
10. Reflections

Editorial Reviews

"This is not only a study of Kreb's research, it is also a comprehensive biography of Kreb's personal as well as scientific life....comprehensive....excellent....Holmes gives a penetrating analysis of Kreb's mode of research, its strength and its limitations. These two volumes represent an extraordinary achievement. The story of both the man and the science is full and rewarding....these volumes, taken together, form one of the greatest of scientific biographies....I know of nothing in the least comparable with Holmes's achievement here, in its depth and breadth." —Nature

"Volume 1 covers Krebs's early life and education, including the beginnings of his research career....Volume 2 covers the time from his arrival in England to publication of the paper on the citric acid cycle in 1937....These volumes have much to say to specialist and nonspecialist alike about the craft of history and the nature of twentieth-century science." —American Historical Review

"In the second volume of this biography Holmes maintains a tone and emphasis equal to that which he established in the first. An important contribution to the literature on the creative process. A well-referenced study, recommended for advanced undergraduate through faculty." —Choice

From reviews of Vol. 1: "In this large first volume of what will be a colossal biography, Holmes reconstructs the education and early career of a remarkable scientist with equally remarkable clarity, comprehensiveness, and detail....This magnificent biography demonstrates, as few books do, the intimate relations between personality and science." —Science

"A remarkable and detailed account of a significant period in the development of biochemistry, reflected in the work of a major 'architect'..." —JAMA

"Meticulous and superb scholarship-grounded in laboratory notebooks, correspondence, published scientific papers, biographical materials, and interviews...." —Journal of the History of Biology

From the Publisher