Carole worked as a graphist and animator for TV programs, before she published her first graphic novel "Les Chroniques Mauves", a collective work about the lesbian community. She has since published several graphic novels, always a characteristic mix of feminine sensibilities and humor.
Tamaki has worked as a writer and performance artist in Toronto, including with Keith Cole's Cheap Queers and in the performance group Pretty Porky & Pissed Off with Joanne Huffa, Allyson Mitchell, Abi Slone, Tracy Tidgwell and Zoe Whittall.[5]
Tamaki published the novel Cover Me in 2000. It is a "poignant story about an adolescent coping with depression". Told in a series of flashbacks, it is about a teenager dealing with cutting and feeling like an outsider in school.[6]
Skim, a collaboration with her cousin Jillian Tamaki, published in 2008 by Groundwood Books, is a graphic novel about a teenage girl and her romantic feelings towards her female teacher; the reciprocity of those feelings remains unclear in the text. The other central story is about the suicide of a classmate's ex-boyfriend who may have been gay. The text is fundamentally "about living in the moments of wrenching transition ...[and] the conflicting need to belong and desire to resist".[7] Tamaki says she did not set out to "make a statement about queerness and youth": "Skim's in love, and kisses a woman, but heck, she's just a kid. She could go on to kiss many people in her future - some of them might be dudes, who knows? I think Skim is more a statement about youth, and the variety of strange experiences that can encapsulate."[8] According to one reviewer, "the expressionistic fluidity of the black and white illustrations serves the purpose of pages of prose"; there is little plot and spare dialogue.[7] Tamaki writes that artists such as Hergé, Igort and Vittorio Giardino as well as Asian art had an influence on her style but her storytelling was rooted in American comics like Daniel Clowes, Chester Brown, and Will Eisner.[9] Skim was originally developed as a short play for Nightwood Theatre.[10]
Emiko Superstar, Tamaki's second graphic novel and first with illustrator Steve Rolston, is about young woman who feels trapped in her suburban life. It was inspired by performance art and Girlspit, an open mic night event in Montreal.[8] The protagonist is inspired to try performance art after visiting such a space. As one review says, "this is a story about finding oneself, one's voice, and one's true character amidst the trappings of counter-culture fame".[11]
In 2014 Tamaki again collaborated with her cousin Jillian Tamaki, on the graphic novel This One Summer, published by Groundwood Books.
In 2016 it was announced that Tamaki would be writing a new Hulk series starring She-Hulk for Marvel Comics,[12] and the mini-series Supergirl: Being Super for DC Comics.
