Organic Chemistry

by Marc Loudon, Nikolaus Julius Weichselbaumer

Overview

Loudon and Parise's Organic Chemistry is known for its clear writing, high standard of accuracy, and creative problems. This edition contains over 1,800 problems—many of them new and taken directly from the scientific literature. The book is used at a wide variety of schools, such as UC Berkeley, Caltech, Colorado, Cornell, Duke, Harvard, Illinois, Maryland, Purdue, Yale, Wisconsin, and many more. This edition provides students with more health examples drawn from modern medical practice, as well as many cutting-edge topics from modern synthetic organic chemistry.

In addition to the printed book, students can rely on Sapling Learning’s online homework platform for extra learning and assessment. The platform offers automatic grading, an easy-to-use interface, and instructive feedback. Instructors can select from a variety of existing problem sets—over 1,000 of Loudon's problems are in the platform!—or they can modify the questions or author them from scratch. Not only does the software allow students to easily draw and interact with structures, it allows them to draw entire reaction mechanisms, including showing the movement of electrons with curved electron arrows.

Product Details

ISBN-13:	9781936221349
Publisher:	MacMillan Higher Education
Publication date:	05/28/2015
Edition description:	New Edition
Pages:	1648
Product dimensions:	8.70(w) x 11.20(h) x 2.10(d)
Age Range:	18 Years

About the Author

Marc Loudon is the Cwalina Distinguished Professor of Medicinal Chemistry at Purdue Univerity. His teaching awards include the Clark Teaching Prize (at Cornell), Purdue’s School of Pharmacy's Henry Heine Outstanding Teacher Award (1980 and 1985), the Class of 1922 Helping Students Learn Award, the Charles B. Murphy Award, membership in the Teaching Academy of Purdue and listing in Purdue’s permanent “Book of Great Teachers”, and designation as the Carnegie Foundation “Indiana Professor of the Year”. Most recently, Dr. Loudon has been involved in chemistry curriculum re-design for life-science majors and pre-health profession students with the NEXUS program of the Howard Hughes Medical Institute.

James Parise is a Teaching Professor in the Department of Chemistry and Biochemistry at the University of Notre Dame, where he lectures organic chemistry. Previously, he taught and coordinated organic chemistry laboratories at Duke University. Dr. Parise’s research interests include development of more effective teaching methods for large lecture courses and improving organic chemistry pedagogy in both the classroom and laboratory. He administers an instructor-training program in organic chemistry and is currently developing auxiliary courses aimed at supplementing student preparation for introductory organic courses.

Table of Contents

1. Chemical Bonding and Chemical Structure

2. Alkanes

3. Acids and Bases. The Curved-Arrow Notation

4. Introduction to Alkenes: Structure and Reactivity

5. Addition Reactions of Alkenes

6. Principles of Stereochemistry

7. Cyclic Compounds: Stereochemistry of Reactions

8. Noncovalent Intermolecular Interactions

9. The Chemistry of Alkyl Halides

10. The Chemistry of Alcohols and Thiols

11. The Chemistry of Ethers, Epoxides, Glycols, and Sulfides

12. Introduction to Spectroscopy: Infrared Spectroscopy and Mass Spectrometry

13. Nuclear Magnetic Resonance Spectroscopy

14. The Chemistry of Alkynes

15. Dienes, Resonance, and Aromaticity

16. The Chemistry of Benzene and its Derivatives

17. Allylic and Benzylic Reactivity

18. The Chemistry of Aryl Halides, Vinylic Halides, and Phenols. Transition-Metal Catalysis.

19. The Chemistry of Aldehydes and Ketones. Carbonyl-Addition Reactions.

20. The Chemistry of Carboxylic Acids

21. The Chemistry of Carboxylic Acid Derivatives

22. The Chemistry of Enolate Ions, Enols, and a,b- Unsaturated Carbonyl Compounds

23. The Chemistry of Amines

24. Carbohydrates

25. The Chemistry of Thioesters, Phosphate Esters, and Phosphate Anhydrides

26. The Chemistry of the Aromatic Heterocycles; DNA

27. Amino Acids, Peptides, and Proteins

28. Pericyclic Reactions

Editorial Reviews

We have used a number of editions of Loudon for our second year organic course. Although each edition has represented a major advance in the presentation of new chemistry, they have all retained the lucid presentation and order of topics that attracted us to the first version. The problems and examples provide excellent reinforcement of the contents of each chapter. The inclusion of modern methodology in the newest edition will prepare students for graduate school and demonstrates the continuing evolution of organic chemistry.” —Robert H. Grubbs, California Institute of Technology

“My colleagues and I have used the Loudon text here at Harvard for a number of years. The latest edition of this textbook refines the author's approach to the teaching of organic chemistry on a mechanism-based approach that was first introduced by Cram and Hammond more than 50 years ago. I consider it one of the premier texts of this generation.” —David Evans, Harvard University

“This text continues to refine the author's characteristically elegant, mechanism-based framework for introducing organic chemistry. Professor Loudon has inspired several generations of students with his clear and insightful presentation style. In no other text does the logic, power and sheer beauty of organic chemistry shine through so clearly.”  —Bruce Ganem, Cornell University

“This book is simply marvelous. It has plenty of stimulating illustrations and examples, and its many problems progress gradually from trivial to challenging and instructive. But, most importantly, its exposition is rock-solid, full of the lucid analogies and consistent mechanistic logic that make organic chemistry tractable.”  —AMAZON (a student at Caltech)

“From over thirty years in the classroom, Marc Loudon knows how students learn. His problems are the work of a master teacher; they are original, range in difficulty levels, and are all based on real examples from the literature. This edition is clearly a labor of love and reflects Professor Loudon’s desire to give students the very best learning tool possible. This book is a symphony of great ideas and will open students’ eyes to the wonders of modern organic chemistry.” —John Grutzner, Purdue University

From the Publisher