Pride and Prejudice (Jane Austen Collection)

by Jane Austen

Overview

Autoimmune disorders are amongst the most frequently encountered conditions in endocrine practice. The evidence-based approach to therapeutics and detailed evaluation of the outcome of existing treatment regimens have led to some advances in care delivery. Pragmatic reviews by leading international experts outline the clinical state of the art in several chapters of this issue of the Endocrinology and Metabolism Clinics of North America devoted to autoimmune disorders. Topics covered include the following: regulatory T cells as key players in tolerance and autoimmunity; immunology lessons from monogenic conditions such as AIRE; immunogenetics of T1D and AITD; advances in T1D therapeutics, including islet cell replacement and salvage; updates on TSHR structure, function, and monoclonal human TSHR antibodies; animal models of Grave’s disease; evidence-based and emerging modalities of treatment of Graves’ hyperthyroidism; patient selection and treatment of thyroid-associated ophthalmopathy; antibodies to steroidogenic tissues: Addison’s and POF; diagnosis and management of polyendocrinopathy syndromes; autoimmune parathyroid disease; and autoimmune hypophysitis.

Product Details

ISBN-13:	9780785294634
Publisher:	Harper Muse
Publication date:	03/14/2023
Pages:	464
Product dimensions:	6.00(w) x 9.00(h) x 0.00(d)

About the Author

In 1801, George Austen retired from the clergy, and Jane, Cassandra, and their parents took up residence in Bath, a fashionable town Jane liked far less than her native village. Jane seems to have written little during this period. When Mr. Austen died in 1805, the three women, Mrs. Austen and her daughters, moved first to Southampton and then, partly subsidized by Jane's brothers, occupied a house in Chawton, a village not unlike Jane's first home. There she began to work on writing and pursued publishing once more, leading to the anonymous publication of Sense and Sensibility in 1811 and Pride and Prejudice in 1813, to modestly good reviews.

Known for her cheerful, modest, and witty character, Jane Austen had a busy family and social life, but as far as we know very little direct romantic experience. There were early flirtations, a quickly retracted agreement to marry the wealthy brother of a friend, and a rumored short-lived attachment -- while she was traveling -- that has not been verified. Her last years were quiet and devoted to family, friends, and writing her final novels. In 1817 she had to interrupt work on her last and unfinished novel, Sanditon, because she fell ill. She died on July 18, 1817, in Winchester, where she had been taken for medical treatment. After her death, her novels Northanger Abbey and Persuasion were published, together with a biographical notice, due to the efforts of her brother Henry. Austen is buried in Winchester Cathedral.

Author biography courtesy of Barnes & Noble Books.

Date of Birth:

December 16, 1775

Date of Death:

July 18, 1817

Place of Birth:

Village of Steventon in Hampshire, England

Place of Death:

Winchester, Hampshire, England

Education:

Taught at home by her father