He left England before the end of the year for Basel, where the greater part of his life thenceforth was passed. Froben had made Basel the chief literary centre of production for the whole of Europe. Through Froben's printing-presses Erasmus could reach a wider audience than was allowed him at any court, however favourable to pure religion and the new learning. It was at this juncture that he made an eloquent and far-reaching appeal, on a matter which lay very near his heart, to the conscience of Christendom.