Clinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic, Nutritional and Deposition Disease / Edition 1

by Bruce R. Smoller, Franco Rongioletti

Overview

Through a unique presentation of clinical photographs and accompanying histologic photomicrographs, Clinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic, Nutritional and Deposition Disease provides the practicing surgical pathologist, dermatologist, endocrinologist, internal medicine physician and dermatopathologist with a single volume source that reviews the clinical and pathologic features of metabolic and endocrine disorders that display cutaneous manifestations. Color photographs are presented for each condition followed by a series of phoromicrographs depicting each entity microscopically. The text includes Clinical Features, Pathology, Etiopathogenesis, Differential Diagnosis and Therapy for all entities, described in a clear, concise style. In-depth discussions of the clinical findings, as well as the histologic features of these diseases are included. Additionally, laboratory data used to make and support the diagnoses is discussed for each entity. The first section covers metabolic disorders that have cutaneous manifestations. Diseases organized by the endocrine organ primarily responsible for the systemic condition are covered. For each entity, an atlas of clinical manifestations is presented that will serve as a bed-side clinical reference, followed by a series of photomicrographs depicting the histologic changes. This unique format of presentation is followed throughout the volume in the second through fourth sections addressing Metabolic Diseases, Nutritional Disorders that affect the skin and finally Cutaneous Deposition Disorders. Clinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic, Nutritional and Deposition Disease is a unique reference for the practicing dermatopathologist, general pathologist reviewing skin biopsies, general dermatologists, internists and endocrinologists.

Product Details

ISBN-13:	9781607611806
Publisher:	Springer New York
Publication date:	10/01/2010
Edition description:	2010
Pages:	195
Product dimensions:	8.20(w) x 11.10(h) x 0.60(d)

Table of Contents

Part I. CUTANEOUS ENDOCRINE DISEASE
1. ADRENAL DISEASE
Kennet Calder/Bruce Smoller

1.1.Cushing's syndrome
1.2.Addison's disease
1.3.Pheocromocytoma

2. PANCREAS DISEASE AND DIABETES MELLITUS
Franco Rongioletti

2.1. Non infectious skin manifestations
2.1.1 Necrobiosis lipoidica
2.1.2 Diabetic dermopathy
2.1.3 Granuloma annulare
2.1.4 Diabetic thick skin
2.1.5 Bullosis diabeticorum
2.1.6 Eruptive xanthomas
2.1.7 Acquired perforating dermatosis
2.1.8 Acanthosis nigricans
2.1.9 Miscellanea
2.2 Cutaneous infections
2.2.1 Bacterial Infections
2.2.2 Candida Infections
2.2.3 Dermatophyte Infections
2.2.4 Rare infections
2.3 Complications due to diabetic neuropathy and vasculopathy
2.4 Complications due to diabetes treatment

3. THYROID DISEASE
Alfredo Rebora/Franco Rongioletti
3.1.Hyperthyroidism
3.2.Hypothyroidism

4. PITUITARY GLAND DISEASE
Martina Montinari/Franco Rongioletti
4.1. Acromegaly
4.2. Hyperprolactinemia
4.3 Cushing’s disease
4.4 Panhypopituitarism

5. PARATHYROID DISEASE
Yann Charli-Joseph/Marcela Saeb-Lima
5.1.Hyperparathyroidism
5.1.1 Familial (hereditary) forms of primary hyperparathyroidism
5.1.2 Hyperparathyroidism related to renal failure
5.1.3 Other cutaneous manifestations
5.2. Hypoparathyroidism

Part II.CUTANEOUS METABOLIC DISEASE

6. DYSLIPIDEMIA (HYPERLIPIDEMIA)
Terry Katona/Bruce Smoller
6.1 Specific xanthomas
6.1.1 Planar xanthomas
6.1.2 Eruptive xanthomas
6.1.3 Tuberous xanthomas
6.1.4 Tendinous xanthomas
6.1.5 Cholesterotic fibrous histiocytoma

7. GOUT
Uma Sundram
8.LIPOMATOSIS
Uma Sundram
8.1 Diffuse lipomatosis
8.2 Familial multiple lipomatosis
8.3 Multiple symmetric lipomatosis
8.4 Adiposis dolorosa (Dercum’s disease)
8.5 Syndromes that can demonstrate multiple lipomas
8.5.1 Proteus syndrome
8.5.2 Bannayan-Zonana syndrome

9.OBESITY
Jessica Linder/Amena Usmani/Maria Miteva/Camillo Ricordi/Paolo Romanelli
9.1 Achrocordons
9.2 Adiposis dolorosa
9.3 Hidradenitis suppurativa
9.4 Lymphedema
9.5Acanthosis nigricans
9.6 Strie distensae
9.7 Hyperandrogenism
9.8 Plantar hyperkeratosis
9.9 Other skin manifestations

10.PORPHYRIAS
Jaqueline Junkins-Hopkins
10.1 Congenital erythropoietic porphyria (CEP)
10.2 Porphyria cutanea tarda
10.3 Erythropoietic protoporphyria
10.4 Hepatoerythropoietic porphyria
10.5 Pseudoporphyria

11.HEMOCHROMATOSIS
Aurora Parodi/Franco Rongioletti
12.THE METABOLIC SYNDROME IN PSORIASIS
Paolo Gisondi/GiampieroGirolomoni

III. CUTANEOUS NUTRITIONAL DISEASE

13.ACQUIRED NUTRITIONAL DEFICIENCIES
Martina Montinari/Aurora Parodi/Franco Rongioletti
13.1 Scurvy
13.2 Acquired acrodermatitis enteropatica (dermatitis associated with zinc deficiency)
13.3 Pellagra
13.4 Iron deficiency
13.5 Other nutritional deficiencies

14.ANOREXIA NERVOSA
Jameel Ahmad Brown
14.1 Xerosis
14.2 Lanugo-like body hairs
14.3 Alopecia
14.4 Hypercarotenemia/Carotenoderma

14.5 Acne
14.6 Acrocyanosis
14.7 Pruritus
14.8 Purpura
14.9 Nail Changes
14.10 Angular Cheilitis
14.11 Russell’s Sign
14.12 Finger Clubbing, fixed drug eruption, and photosensitivity dermatitis

14.13 Miscellanea

15.ALCOHOL ABUSE
Torello Lotti/ Angelo Massimiliano D’Erme
15.1 Skin diseases significantly associated with alcoholism
15.2 Nutritional and metabolic diseases with skin symptoms induced by alcoholism
15.3 Skin diseases exacerbated by alcohol

16.GLUCAGONOMA SYNDROME AND NECROLYTIC MIGRATORY ERYTHEMA
Franco Rongioletti

IV. CUTANEOUS DEPOSITION DISEASE
17. AMYLOIDOSES
Franco Rongioletti
17.1 Acquired systemic amylodoses with cutaneous involvement
17.1.1 Primary and myeloma-associated amyloidosis (AL amyloidosis)
17.1.2 Secondary systemic AA amyloidosis
17.1.3— 2-Microglobulin hemodialysis-associated amyloidosis

17.2. Hereditary/familial systemic amyloidoses with cutaneous involvement
17.3. Localized cutaneous amyloidoses

17.3.1 Primary localized cutaneous amyloidoses
17.3.2. Secondary localized cutaneous amyloidosis

18.MUCINOSES
Franco Rongioletti
18.1

Editorial Reviews

Reviewer: Patricia Wong, MD (Private Practice)
Description: This reader-friendly book nicely correlates clinical skin abnormalities with what is seen histologically. Numerous color clinical photographs appear adjacent to the microscopic photographs so one can understand why we observe these changes. There are succinct short discussions on clinical findings, including helpful diagnostic tips for distinguishing among similarly appearing conditions. Brief but informative paragraphs summarize pathophysiology, immunological dysfunction, and associated organ system problems well.
Purpose: The purpose is to enlighten dermatologists and pathologists on endocrine, metabolic, nutritional, and deposition disease changes seen clinically and microscopically.
Audience: The audience is dermatologists and pathologists. The material is presented in an easy to digest format, and residents in training would benefit from the book.
Features: Numerous helpful tables list clinical findings seen with particular endocrine disorders. Diagrams outlining enzymatic defects, when applicable, are simple to understand and devoid of too many arrows and boxes. The book's strength lies in its clear presentations of the clinical findings that a dermatologist would encounter with these diseases, the very good clinical photographs, and the summaries of the highlights of each condition. The book does not try to be an exhaustive tome on the subject and, therefore, is an excellent starting point before embarking further for more in-depth information if necessary.
Assessment: This book offers a good, basic understanding of clinical and histologic findings, which enables readers to understand the pathology and the skin change signs. This makes it easier to visualize what is visible to the naked eye and understand conceptually what is represented microscopically.

Doody's Review Service