Structures and Mechanisms: From Ashes to Enzymes

by Gareth R. Eaton, Don C. Wiley, Oleg Jardetzky

Overview

This volume encompasses a wide range of chemistry, with juxtaposition of, for example, boron hydrides, quantum mechanical calculations, and structure of a virus, providing a perspective on chemistry not offered by traditional texts. The breadth of this book will be stimulating and cause readers to think a little beyond the usual confines of a particular research field. The book begins with an autobiographical reflection by Lipscomb and includes an introduction to the science of William N. Lipscomb. This volume encompasses a wide range of chemistry, with a juxtaposition of, for example, boron hydrides, quantum mechanical calculations, and structure of a virus, providing a perspective on chemistry not offered by traditional texts. The volume includes chapters on polyhedral boranes, oscillations, waves, and patterns in chemistry and biology, interference of atom lasers, chemical theory of bonding and NMR parameters, NMR and EPR of proteins, biological energy transduction, protein-ligand interactions, and relation of structures to the central dogma of biology, and concludes with comments on the relation of the retrovirus core to the function of this molecular machine.

Product Details

ISBN-13:	9780841237360
Publisher:	American Chemical Society
Publication date:	01/28/2002
Series:	ACS Symposium Series , #827
Pages:	432
Product dimensions:	9.10(w) x 6.20(h) x 0.90(d)

About the Author

University of Denver

Harvard University

Stanford University

Table of Contents

Preface
Process of Discovery (1977); an Autobiographical Sketch, William N. Lipscomb
Introduction
1. The Landscape and the Horizons: An Introduction to the Science of William N. Lipscomb, Gareth R. Eaton
Inorganic Chemistry
2. Thomas Jefferson, Alice in Wonderland, Polyhedral Boranes, and the Lipscomb Legacy, Russell N. Grimes
3. Recent Developments in the Chemistry of Main Group Metallacarboranes of the C[2B[4-Carborane Ligands, Narayan S. Hosmane and John A. Maguire
4. Formation of Nanostructured Phases of Fe, Co, and Ni by a Freeze-Out Technique, Kimloan T. Nguyen, Alfred A. Zinn, and Herbert D. Kaesz
5. Proposed New Materials: Boron Fullerenes, Nanotubes, and Nanotori, Vladimir Dadashev et al.
6. Oscillations, Waves, and Patterns in Chemistry and Biology, Irving R. Epstein
Theory
7. Electron Propagator Theory of Ionization Energies and Dyson Orbitals for µ-Hydrido, Bridge-Bonded Molecules: Diborane, Digallane, and Gallaborane, Gustavo Seabra, V. G. Zakrzewski, and J. V. Ortiz
8. Application of Theoretical Methods to NMR Chemical Shifts and Coupling Constants, Michael L. McKee
9. Does the Magnitude of NMR Coupling Constants Specify Bond Polarity?, Rodney J. Bartlett, Janet E. Del Bene, and S. Ajith Perera
10. Aluminosilicate Inorganic Compounds, Minerals, and Mineral Glasses: Connections Forged by Quantum Chemistry and NMR Spectroscopy, John A. Tossell
11. Bragg Diffraction and the Interference of Two Atom Lasers: An Analogy, Roger A. Hegstrom
Protein, DNA, and Viruses
12. B[1[2-Dependent Methionine Synthase: a Structure that Adapts to Catalyze Multiple Methyl Transfer Reactions, Martha L. Ludwig and Rowena G. Matthews
13. Metalloproteins to Membrane Proteins: Biological Energy Transduction Mechanisms, Douglas C. Rees
14. Paradigms for Protein-Ligand Interactions, Florante A. Quiocho
15. Structures of the Central Dogma of Molecular Biology, Thomas A. Steitz
16. Analysis of Intradomain Signaling in the Multifunctional Protein CAD Using Novel Hybrids and Chimeric Molecules, David R. Evans and Hedeel I. Guy
17. A New Engine for Cleaving Nucleic Acid, Kurt L. Krause and Mitchell D. Miller
18. Activation of Hematopoiesis and Vasculogenesis in the Mouse Embryo: Induction and Reprogramming of Ectodermal Cell Fate by Signals from Primitive Endoderm, Margaret H. Baron
19. Scoring Functions Sensitive to Alignment Error Have a More Difficult Search: a Paradox for Threading, Jeffrey Chang et al.
20. Electron Paramagnetic Resonance Techniques for Measuring Distances in Proteins, Sandra S. Eaton and Gareth R. Eaton
21. Allostery and Induced Fit: NMR and Molecular Modeling Study of the trp Repressor-mtr DNA Complex, Luciano Brocchieri, Guo-Ping Zhou, and Oleg Jardetzky
22. The 3.6 OA Structure of the Reovirus Core Particle, Karin M. Reinisch and Stephen C. Harrison
Author Index
Subject Index